The Interior of the Lexus LS are as follow:
| Variants | 2018 Lexus LS LS 500 Executive | 2018 Lexus LS LS 500 Luxury | 2018 Lexus LS LS 500h Executive |
| Sunroof | Yes | Yes | Yes |
| Sunshade | Powered Rear Sun Shade and Rear Door Window Shades | Powered Rear Sun Shade and Rear Door Window Shades | Powered Rear Sun Shade and Rear Door Window Shades |
| Seat Features(Front-Driver) | 28-Way Power Adjustable Seats with Memory Function | 28-Way Power Adjustable Seats with Memory Function | 28-Way Power Adjustable Seats with Memory Function |
| Seat Features(Passenger) | |||
| Seat Features(Rear) | 22-way Power Adjustable Seats with Passenger Side Ottoman, Centre Armrest, Rear Touchscreen, Heating, Cooling and Massage | 18-way Power Adjustable Seats with Centre Armrest, Rear Touchscreen, Heating and Ventilation | 22-way Power Adjustable Seats with Passenger Side Ottoman, Centre Armrest, Rear Touchscreen, Heating, Cooling and Massage |
| Cupholders | 2 Front, 2 Rear | 2 Front, 2 Rear | 2 Front, 2 Rear |
| Front Air-con | Dual-zone Automatic Climate Control System | Dual-zone Automatic Climate Control System | Dual-zone Automatic Climate Control System |
| Rear Air-con | Y | Y | Y |
| Paddle Shift | Y | Y | Y |
| Multi-function Steering Wheel | Y | Y | Y |
| Steering Tilt | Y | Y | Y |
| Steering Telescopic | Y | Y | Y |
| Steering Adjustment Electric | Y | Y | Y |
| Engine Start | Keyless Push Button | Keyless Push Button | Keyless Push Button |
| Head-up Display | Y | Y | Y |
